88234-27-9Relevant academic research and scientific papers
Complexes of silicon and phosphorus chlorides with nitrogen-containing bases as the condensing agents in the synthesis of amides
Besgubenko, L. V.,Pipko, S. E.,Sinitsa, A. D.
, p. 1382 - 1390,9 (2020/09/16)
High effectiveness of new condensing agents on the basis of complexes of silicon and phosphorus chlorides with nitrogen-containing bases in the synthesis of amides from carboxylic acids and amines and also in heterocyclization is shown. Factors affecting the readiness of formation of the amide bond and the yields of the final products are established.
Synthesis and structure of complexes of phosphorus pentachloride with 4-dimethylaminopyridine and n-methylimidazole
Pipko, Sergey E.,Bezgubenko, Ludmila V.,Sinitsa, Anatoliy D.,Rusanov, Eduard B.,Kapustin, Evgeniy G.,Povolotskii, Mark I.,Shvadchak, Volodymyr V.
, p. 171 - 177 (2008/09/18)
Complexes of phosphorus pentachloride with 4-dimethylaminopyridine and N-methylimidazole were synthesized. The molecular structure of the phosphorus pentachloride complex with N-methylimidazole was determined by single-crystal X-ray diffraction. In the cationic part of the complex, the phosphorus atom possesses four P - Cl bonds within the range 2.109-2.148 A and two cis-P-N bonds (1.811 and 1.832 A) with N-methylimidazole and exhibits slightly distorted octahedral coordination with angles at phosphorus atom in the range 87.57°-91.50°. The relative stability of the cis and trans conformations of the complex was studied by DFT calculations. The chemical properties and reactivity of the compounds obtained are determined; their utility as condensing agents in the synthesis of amides from acids and amines was shown.
