88238-03-3

Upstream product

• 54503-64-9 2,3-O-isopropylidene-5-O-trityl-D-ribofuranose 
• 5975-09-7 2,3-O-isopropylidene-β-D-ribofuranosyl-1-azide 
• 76-83-5 trityl chloride 
• 57274-17-6 2,3-O-isopropylidene-1,5-di-O-(p-nitrobenzoyl)-β-D-ribofuranose 
• 88237-99-4 2,3-O-isopropylidene-5-O-(4-nitrobenzoyl)-β-D-ribofuranosyl azide 

Relevant academic research and scientific papers

STEREOSELECTIVE SYNTHESIS OF α-RIBONUCLEOSIDES FROM 1-HYDROXY SUGARS BY USING 2-FLUOROPYRIDINIUM TOSYLATE

A novel method for the preparation of α-ribonucleosides was developed by the use of 2-fluoro-1-methylpyridinium tosylate as a condensing reagent.Various α-ribonucleosides were synthesized from 1-hydroxy sugars and trimethylsilylated nitrogen compounds, such as nucleoside bases and azide, in good yields under mild conditions.

D-RIBOFURANOSYL AZIDES. A DIRECT CONVERSION OF 1-O-ACYL-2,3-O-ISOPROPYLIDENE-D-RIBOFURANOSE INTO D-RIBOFURANOSYL AZIDES

Reactions of azidotrimethylsilane with 1-O-acetyl-2,3,5-tri-o-benzoyl-β-D-ribofuranose (2), and the 1,5-di-O-p-nitrobenzoyl and 1,5-di-O-acetyl derivatives, 4 and 5 respectively, of 2,3-O-isopropylidene-β-D-ribofuranose, in the presence of the Lewis acids