882408-14-2

Upstream product

• 630126-17-9 5-[(6-chloro-4-pyrimidinyl)oxy]-2,3-dihydro-1H-indole 
• 329-01-1 1-isocyanato-3-trifluoromethyl-benzene 

Downstream Products

• 882405-23-4 5-{6-[3-(4-methylpiperazin-1-yl)-propylamino]-pyrimidin-4-yloxy}-2,3-dihydro-indole-1-carboxylic acid (3-trifluormethyl-phenyl)-amide 
• 882408-09-5 5-(6-azido-pyrimidin-4-yloxy)-2,3-dihydro-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide 
• 882405-24-5 5-(6-isopropylamino-pyrimidin-4-yloxy)-2.3-dihydro-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide 

Relevant academic research and scientific papers

CYCLIC DIARLY UREAS SUITABLE AS TYROSINE KINASE INHIBITORS

The invention relates to novel compounds of Formula (I): wherein p is 1, 2 or 3; n is 0, 1, 2 or 3; mis0,1,2or3; A is CRc, S, NRc or O, where Rc is H or lower alkyl; X, Y and Z are each independently selected fro N or C-R

DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

The invention relates to the use of diaryl urea derivatives in the treatment of protein kinase dependent diseases or for the manufacture of pharmaceutical compositions for use in the treatment of said diseases, methods of use of diaryl urea derivatives in the treatment of said diseases, pharmaceutical preparations comprising diaryl urea derivatives for the treatment of said diseases, diaryl urea derivatives for use in the treatment of said diseases, novel diaryl urea derivatives, pharmaceutical preparations comprising these novel diaryl urea derivatives, processes for the manufacture of the novel diaryl urea derivatives, the use or methods of use of the novel diaryl urea derivatives as mentioned above, and/or these novel diaryl urea derivatives for use in the treatment of the animal or human body.