882409-43-0

Basic information

• Product Name: (-)-(R)-4-Methyl-1-indalol
• CAS NO: 882409-43-0
• Molecular Weight: 148.205
• Mol File: 882409-43-0.mol

Chemical Properties

• CAS DataBase Reference: (-)-(R)-4-Methyl-1-indalol(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(R)-4-Methyl-1-indalol(882409-43-0)
• EPA Substance Registry System: (-)-(R)-4-Methyl-1-indalol(882409-43-0)

Safety Data

• Hazardous Substances Data: 882409-43-0(Hazardous Substances Data)

Upstream product

• 24644-78-8 4-methylindanone 
• 76-86-8 Triphenylsilyl chloride 
• 67864-03-3 4-methyl-2,3-dihydro-1H-inden-1-ol 

Relevant articles and documents

Silylative Kinetic Resolution of Racemic 1-Indanol Derivatives Catalyzed by Chiral Guanidine

Efficient kinetic resolution of racemic 1-indanol derivatives was achieved using triphenylchlorosilane by asymmetric silylation in the presence of chiral guanidine catalysts. The chiral guanidine catalyst (R,R)-N-(1-(β-naphthyl)ethyl)benzoguanidine was found to be highly efficient as only 0.5 mol % catalyst loading was sufficient to catalyze the reaction of various substrates with appropriate conversion and high s-values (up to 89). This catalyst system was successfully applied to the gram-scale silylative kinetic resolution of racemic 1-indanol with high selectivity.