88243-82-7Relevant academic research and scientific papers
First preparation of single-enantiomer juvenile hormone III acid and (R)-juvenile hormone III-d3
Ichikawa, Akio,Takenaka, Makiko,Ono, Hiroshi
experimental part, p. 1800 - 1806 (2011/02/23)
The (R)- and (S)-enantiomers of juvenile hormone (JH) III acid [(R)-2 and (S)-2] were prepared by the hydrolysis of (R)- and (S)-JH III [(R)-1 and (S)-1], respectively. Each enantiomer of 2 was purified by preparative reversed-phase high performance liquid chromatography in a single operation. (RS)-2 was methylated with CH3I and K2CO3 in MeCN, yielding (RS)-1. (R)-JH III-d3 [(R)-3], a single-enantiomer internal standard for quantification, was prepared from (R)-2 with CD3I and K2CO3 in MeCN.
