88252-59-9

Upstream product

• 326884-52-0 3-nitro-N-(2-phenylethyl)benzamide 
• 14157-05-2 1-(methylsulfanyl)-3,4-dihydroisoquinoline 
• 13331-27-6 m-nitrobenzene boronic acid 
• 6552-60-9 3,4-dihydro-2H-isoquinoline-1-thione 
• 121-90-4 m-nitrobenzoic acid chloride 
• 156-28-5 2-phenylethylamine hydrochloride 

Downstream Products

• 426840-11-1 3-(3,4-dihydro-[1]isoquinolyl)-aniline 
• 583871-54-9 7-Nitro-1-(3-nitrophenyl)-3,4-dihydroisochinolin 
• 88252-53-3 1-(4-Chloro-phenoxy)-9b-(3-nitro-phenyl)-1,4,5,9b-tetrahydro-azeto[2,1-a]isoquinolin-2-one 
• 855653-42-8 7-nitro-1-(3-nitro-phenyl)-isoquinoline 

Relevant academic research and scientific papers

New synthetic approach for the preparation of 1-Aryl-3,4-dihydroisoquinolines by liebeskind-srogl reaction

An efficient synthetic methodology has been developed to construct 1-aryl-3,4-dihydroisoquinoline derivatives. The reaction was performed under neutral conditions by a palladium-catalyzed desulfitative carbon-carbon cross-coupling protocol.

(Dihydro) Isoquinoline derivatives as phosphodiesterase inhibitors

3,4-Dihydroisoquinoline and isoquinoline compounds of formula I, in which Ar represents a phenyl raidcal of the formulae IIa, IIb or IIc are novel effective PDE7 inhibitors.