882525-08-8

Basic information

• Product Name: 4-[(4-chloro-phenyl)-hydroxy-methyl]-4-(diisopropoxy-phosphoryl)-4H-pyridine-1-carboxylic acid ethyl ester
• Synonyms: 4-[(4-chloro-phenyl)-hydroxy-methyl]-4-(diisopropoxy-phosphoryl)-4H-pyridine-1-carboxylic acid ethyl ester
• CAS NO: 882525-08-8
• Molecular Weight: 457.891
• Mol File: 882525-08-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(4-chloro-phenyl)-hydroxy-methyl]-4-(diisopropoxy-phosphoryl)-4H-pyridine-1-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4-chloro-phenyl)-hydroxy-methyl]-4-(diisopropoxy-phosphoryl)-4H-pyridine-1-carboxylic acid ethyl ester(882525-08-8)
• EPA Substance Registry System: 4-[(4-chloro-phenyl)-hydroxy-methyl]-4-(diisopropoxy-phosphoryl)-4H-pyridine-1-carboxylic acid ethyl ester(882525-08-8)

Safety Data

• Hazardous Substances Data: 882525-08-8(Hazardous Substances Data)

Upstream product

• 116-17-6 triisopropyl phosphite 
• 110-86-1 pyridine 
• 104-88-1 4-chlorobenzaldehyde 
• 80891-12-9 diisopropyl-1-ethoxycarbonyl-1,4-dihydropyridine-4-phosphonate 

Downstream Products

• 4409-11-4 4-(4-chlorobenzyl)pyridine 

Relevant articles and documents

Regioselective synthesis of 4-alkylpyridines from pyridine and aldehydes via dipole reversal process of 1,4-dihydropyridine phosphonate

4-Alkylation of pyridine has been accomplished by the reaction of ylides, derivated from 1,4-dihydropyridine phosphonate via phosphonioalkoxycarbonylation of pyridine with aldehydes and subsequent elimination of diisopropyl phosphate followed by aromatization with potassium tert-butoxide.