882529-68-2

Usage

Uses

Used in Pharmaceutical Industry:
Tert-butyl 3-oxo-2,3,6,7-tetrahydro-1H-azepine-1-carboxylate is used as a building block for the synthesis of pharmaceutical drugs and intermediates due to its diverse pharmacological activities and structural characteristics.
Used in Medicinal Chemistry:
Tert-butyl 3-oxo-2,3,6,7-tetrahydro-1H-azepine-1-carboxylate is used as a valuable research tool in medicinal chemistry for drug discovery, leveraging its biological properties and potential applications in the development of new therapeutic agents.
Used in Drug Design and Synthesis:
Tert-butyl 3-oxo-2,3,6,7-tetrahydro-1H-azepine-1-carboxylate is employed in the field of drug design and synthesis to create novel pharmaceutical compounds with potential therapeutic benefits.

Upstream product

• 882529-60-4 tert-butyl but-3-en-1-yl[2-oxo-3-(triphenyl-λ⁵-phosphoranylidene)prop-1-yl]carbamate 
• 882529-64-8 tert-butyl but-3-en-1-yl(2-oxopent-3-en-1-yl)carbamate 

Relevant academic research and scientific papers

AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

Synthesis of 3-oxooxa- and 3-oxoazacycloalk-4-enes by ring-closing metathesis. Application to the synthesis of an inhibitor of cathepsin K

3-Oxooxa- and 3-oxoazacycloalk-4-enes were obtained with good yield from 1-(ω-alkenyloxy)- and 1-(ω-alkenylamino)-but-3-en-2-ones by using a ring-closing metathesis. This methodology has been used to synthesize an inhibitor of cathepsin K.

Synthesis of 3-oxoazacyclohept-4-enes by ring-closing metathesis. Application to the synthesis of an inhibitor of cathepsin K

The ring-closing metathesis allows the formation of 3-oxoazacyclohept-4-enes from but-3-enamine. By using this methodology, the synthesis of an inhibitor of cathepsin K was achieved in 10 steps from but-3-enamine.