88260-07-5Relevant academic research and scientific papers
Synthesis of potential thromboxane A2 antagonists based on the aza-bicycloheptane skeleton
Perrin, Veronique,Riveron, Veronique,Traversa, Christel,Balme, Genevieve,Gore, Jacques
, p. 3121 - 3145 (2007/10/03)
Thirteen compounds having a 2-aza or a 7-aza bicycloheptane framework substituted on carbon-3 by a prostanoic chain have been synthesized starting from easily obtained hetero-Diels Alder adducts. Due to their structure, a TxA2 antagonist
2-Azabicycloheptane-3-carboxylic Acid - A Bicyclic Proline
Gaitanopoulos, Dimitri E.,Weinstock, Joseph
, p. 957 - 959 (2007/10/02)
Diels-Alder reaction of cyclopentadiene and methyl N-carbobenzyloxy-2-iminoacetate generated in situ from methyl 2-chloro-N-carbobenzyloxyglycinate by triethylamine gave the N-carbobenzyloxy unsaturated bicyclic proline ester.This was converted in two ste
Total Synthesis of (+/-)-8-Aza-9a,9b-dicarbaprostaglandin H1
Blondet, Dominique,Morin, Christophe
, p. 1085 - 1090 (2007/10/02)
The total synthesis of a stable prostaglandin H1 analogue in which the bicyclic peroxide system is replaced by a 2-azabicycloheptane ring is described.Appropriate functionalization of the heterocycle and de-ethoxycarbonylation of an α-tr
