882697-72-5Relevant academic research and scientific papers
An [Fe-Fe]-hydrogenase mimic immobilized on MCM-41 for the photochemical production of hydrogen in pure water
Wang, Wen,Yu, Tianjun,Zeng, Yi,Chen, Jinping,Li, Yi
supporting information, p. 479 - 484 (2014/07/08)
A composite proton-reducing catalyst Hy@MCM-41 was created by using a hydrophobic [Fe-Fe]-hydrogenase mimic (Hy) incorporated into the K +-exchanged molecular sieve MCM-41. Hy acts as the active site to generate H2 by reducing H+, and MCM-41 provide a large surface area to maintain the dispersion of Hy and to prevent aggregation and precipitation. Hy@MCM-41 was successfully applied to the light-induced hydrogen production in pure water with an iridium compound [Ir(ppy)2bpy]Cl and triethylamine (TEA) as the photosensitizer and the sacrificial electron donor, respectively, exhibiting good stability and catalytic activity. The present study provides a general strategy for the application of water-insoluble catalysts in pure water by using mesoporous molecular sieves. Copyright
Synthesis and characterization of novel 7-hydroxycoumarin derivatives
Mostafavi,Najjar,Maskani
, p. 423 - 425 (2013/09/02)
The synthesis of several coumarin Mannich bases is described. The reaction of natural 7-hydroxycoumarin with primary amines and two equivalents of formaldehyde in the presence of a base catalyst was studied. Several novel N-substituted angular 9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-ones were synthesized. Different aliphatic and aromatic amines have been used in the reaction, and the corresponding products were obtained with moderate to relatively good yields.
Novel hexacyclic camptothecin derivatives. Part 1: Synthesis and cytotoxicity of camptothecins with an A-ring fused 1,3-oxazine ring
Wang, Sheng,Li, Yuyan,Liu, Yonghui,Lu, Aijun,You, Qidong
supporting information; experimental part, p. 4095 - 4097 (2009/04/07)
A novel series of A-ring modified hexacyclic camptothecin derivatives containing a 1,3-oxazine ring were first designed and synthesized. All of the hexacyclic camptothecins were assayed for in vitro cytotoxicity against nine human cancer cell lines. Among these compounds, 9b and 9c showed most potent cytotoxicity against several cell lines. Particularly, 9c was about 13-fold more potent than camptothecin, and about sixfold more potent than topotecan toward HEPG-2. Furthermore, it was also found that the N-alkyl substituted derivatives were more potent than the N-aryl and N-benzyl substituted compounds against most cell lines.
