882749-05-5

Basic information

• Product Name: N-(4-FLUOROBENZYL)-2-(4-PHENYLPIPERAZINO)ACETAMIDE
• Synonyms: SALOR-INT L293997-1EA;N-(4-FLUOROBENZYL)-2-(4-PHENYLPIPERAZINO)ACETAMIDE;N-[(4-fluorophenyl)methyl]-2-(4-phenylpiperazin-1-yl)acetamide
• CAS NO: 882749-05-5
• Molecular Formula: C19H22FN3O
• Molecular Weight: 327.4
• Mol File: 882749-05-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-FLUOROBENZYL)-2-(4-PHENYLPIPERAZINO)ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-FLUOROBENZYL)-2-(4-PHENYLPIPERAZINO)ACETAMIDE(882749-05-5)
• EPA Substance Registry System: N-(4-FLUOROBENZYL)-2-(4-PHENYLPIPERAZINO)ACETAMIDE(882749-05-5)

Safety Data

• Hazardous Substances Data: 882749-05-5(Hazardous Substances Data)

Upstream product

• 92-54-6 4-phenyl-1-piperazine 
• 190193-10-3 2-bromo-N-(4-fluorobenzyl)acetamide 

Relevant articles and documents

The design and synthesis of 1,4-substituted piperazine derivatives as triple reuptake inhibitors

Novel 1,4-substituted piperazine derivatives 5, Series A and B were designed by fragment analysis and molecular modification of 4 selected piperazine-containing compounds which possess antidepressant activity. We synthesized new 39 analogues of Series A and 10 compounds of Series B, respectively. The antidepressant screening against DA, NE, and serotonin neurotransmitter uptake inhibition was carried out using the Neurotransmitter Transporter Uptake Assay Kit. The compounds in Series B showed relatively higher reuptake inhibitory activity for SERT, NET, and DAT than those in Series A. The length of spacer between the central piperazine core and the terminal phenyl ring substituted at the piperazine ring in Series B seems to exert an important role in the activity.