882856-88-4

Basic information

• Product Name: tert-butyl [(3R,4R)-1-[(6-methylamino)-5-nitropyridin-2-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-yl]carbamate
• Synonyms: tert-butyl [(3R,4R)-1-[(6-methylamino)-5-nitropyridin-2-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-yl]carbamate
• CAS NO: 882856-88-4
• Molecular Weight: 481.475
• Mol File: 882856-88-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl [(3R,4R)-1-[(6-methylamino)-5-nitropyridin-2-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl [(3R,4R)-1-[(6-methylamino)-5-nitropyridin-2-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-yl]carbamate(882856-88-4)
• EPA Substance Registry System: tert-butyl [(3R,4R)-1-[(6-methylamino)-5-nitropyridin-2-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-yl]carbamate(882856-88-4)

Safety Data

• Hazardous Substances Data: 882856-88-4(Hazardous Substances Data)

Upstream product

• 165047-24-5 2,4,5-trifluorobenzaldehyde 
• 882856-64-6 dimethyl 2-cyano-3-(2,4,5-trifluorophenyl)pentanedioate 
• 888321-36-6 ethyl 3-(2,4,5-trifluorophenyl)acrylate 
• 882856-76-0 tert-butyl (3R,4R)-1-benzyl-4-(2,4,5-trifluorophenyl)piperidin-3-ylcarbamate 
• 882856-58-8 tert-butyl(3R,4R)-4-(2,4,5-trifluorophenyl)piperidin-3-ylcarbamate 
• 33742-70-0 6-chloro-N-methyl-3-nitropyridin-2-amine 

Relevant articles and documents

Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors

Substituted 3-aminopiperidines 3 were evaluated as DPP-4 inhibitors. The inhibitors showed good DPP-4 potency with superb selectivity over other peptidases (QPP, DPP8, and DPP9). Selected DPP-4 inhibitors were further evaluated for their hERG potassium ch