88287-63-2

Upstream product

• 88287-62-1 1-Acetamido-2,5-anhydro-1,3-dideoxy-D-ribo-hexitol 
• 100-44-7 benzyl chloride 
• 88287-61-0 1-Amino-2,5-anhydro-1,3-dideoxy-4,6-di-O-p-toluyl-D-ribo-hexitol hydrochloride 
• 88287-60-9 1-Acetamido-2,5-anhydro-1,3-dideoxy-4,6-di-O-p-toluyl-D-ribo-hexitol 
• 50908-41-3 2,5-anhydro-3-deoxy-4,6-di-O-toluoyl-D-ribohexononitrile 

Downstream Products

• 88287-64-3 2,5-Anhydro-4,6-di-O-benzyl-1,3-dideoxy-1-(nitrosoacetamido)-D-ribo-hexitol 
• 88287-65-4 2,5-Anhydro-4,6-di-O-benzyl-1,3-dideoxy-1-diazo-D-ribo-hexitol 
• 88287-78-9 4-Amino-3-(3,5-di-O-benzyl-2-deoxy-β-D-erythro-pentofuranosyl)pyrazole-5-carbonitrile 
• 88287-74-5 3-(3,5-Di-O-benzyl-2-deoxy-β-D-erythro-pentofuranosyl)-5-cyanopyrazole-4-carboxylic acid 
• 88287-81-4 3-(3,5-Di-O-benzyl-β-D-erythro-pentofuranosyl)-4-aminopyrazole-5-carbothiamide 
• 88287-71-2 Methyl 3-(3,5-di-O-benzyl-2-deoxy-β-D-erythro-pentofuranosyl)-5-cyanopyrazole-4-carboxylate 
• 88287-68-7 Methyl 3-(3,5-di-O-benzyl-2-deoxy-β-D-erythro-pentofuranosyl)-5-carbamoylpyrazole-4-carboxylate 
• 88287-88-1 3-(3,5-Di-O-benzyl-2-deoxy-β-D-erythro-pentofuranosyl)-5-aminopyrazolo<4,3-d>pyrimidine-7-thione 
• 88287-66-5 Dimethyl 3-(3,5-di-O-benzyl-2-deoxy-β-D-erythro-pentofuranosyl)pyrazole-4,5-dicarboxylate 
• 88287-76-7 3-(3,5-Di-O-benzyl-2-deoxy-β-D-erythro-pentofuranosyl)-4-<<(2,2,2-trichlorethoxy)carbonyl>amino>pyrazole-5-carbonitrile 

Relevant academic research and scientific papers

Synthesis of 3-Glycofuranosyl-5-aminopyrazolopyrimidine-7-thiones: Thioguanosine-Type C-Nucleosides

The first C-nucleosides of the thioguanosine type are the 3-β-D-ribofuranosyl, 3-β-D-arabinofuranosyl, and 3-(2-deoxy-β-D-erythro-pentofuranosyl)derivatives of 5-aminopyrazolopyrimidine-7-thione.Synthesis of these products employed C6H5CH2SC(Cl)=NCOC6H5 as a new reagent for ring closure of the 3-glycofuranosyl-4-aminopyrazole-5-carbothiamide precursors.The new ring closure requires fewer steps and minimizes side reactions encountered in previous guanosine ring closure.The amino thioamide precursors are prepared from pyrazole C-nucleosides available as in previous formycin syntheses.