88299-10-9

Upstream product

• 186581-53-3 diazomethane 
• 88299-06-3 (E)-2-methyl-4-(1-tosyl-1H-indol-4-yl)but-3-en-2-ol 
• 88246-05-3 (E)-4-(1-tosyl-1H-indol-4-yl)but-3-en-2-one 
• 112152-12-2 4--3-buten-2-one 
• 88299-09-6 4-Methyl-N-{(R)-((R)-2,2,5,5-tetramethyl-[1,3]dioxolan-4-yl)-[1-(toluene-4-sulfonyl)-1H-indol-4-yl]-methyl}-benzenesulfonamide 

Downstream Products

• 88299-01-8 (R)-6-((R)-5,5-Dimethyl-2-thioxo-[1,3]dioxolan-4-yl)-5-(toluene-4-sulfonyl)-5,6-dihydro-1H-azepino[5,4,3-cd]indole-4-carboxylic acid methyl ester 
• 88299-00-7 (R)-6-((R)-5,5-Dimethyl-2-oxo-[1,3]dioxolan-4-yl)-5-(toluene-4-sulfonyl)-5,6-dihydro-1H-azepino[5,4,3-cd]indole-4-carboxylic acid methyl ester 
• 88298-99-1 (R)-6-((R)-2,2,5,5-Tetramethyl-[1,3]dioxolan-4-yl)-5-(toluene-4-sulfonyl)-5,6-dihydro-1H-azepino[5,4,3-cd]indole-4-carboxylic acid methyl ester 
• 88299-02-9 (S)-6-((S)-1,2-Dihydroxy-2-methyl-propyl)-5-(toluene-4-sulfonyl)-5,6-dihydro-1H-azepino[5,4,3-cd]indole-4-carboxylic acid methyl ester 
• 88299-03-0 6-(2-Methyl-propenyl)-5-(toluene-4-sulfonyl)-5,6-dihydro-1H-azepino[5,4,3-cd]indole-4-carboxylic acid methyl ester 
• 33062-26-9 (+/-)-4,6-cis-clavicipitic acid 
• 33062-26-9 (+/-)-4,6-trans-clavicipitic acid 
• 88299-11-0 [[(S)-(3-Formyl-1H-indol-4-yl)-((S)-2,2,5,5-tetramethyl-[1,3]dioxolan-4-yl)-methyl]-(toluene-4-sulfonyl)-amino]-acetic acid methyl ester 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF (+/-)-CLAVICIPITIC ACIDS I AND II

Ergot alkaloids, clavicipitic acids (3 and 4) were synthesized respectively in racemic forms from 4-(3-oxo-1-butenyl)-indole (5) by way of (6) and (7).Names of clavicipitic acids I and II were proposed for 3 and 4.