88299-99-4Relevant academic research and scientific papers
Reactivity of 1,2-O-cyanoalkylidene sugar derivatives in trityl-cyanoalkylidene condensation
Kitov, P. I.,Tsvetkov, Yu. E.,Backinowsky, L. V.,Kochetkov, N. K.
, p. 1423 - 1428 (2007/10/02)
The rate-determining step of trityl-cyanoalkylidene condensation is the interaction between the cyanoalkylidene derivative (CD) and the triphenylmethyl cation.The rate of the reaction follows first-order kinetics with respect to both CD and the catalyst (Tr+) and is independent of the nature and condensation of the trityl ether.Glycosylation rate constants have been determined for CD's most common monosaccharides. - Key words: trityl-cyanoalkylidene condensation; cyanoalkylidene derivatives, mechanism of glycosidation.
