883025-91-0Relevant academic research and scientific papers
Synthesis of dihydropyrimidinones via Biginelli multi-component reaction
Narahari, Srinivasa Reddy,Reguri, Buchi Reddy,Gudaparthi, Omprakash,Mukkanti
, p. 1543 - 1545 (2012)
Five percentage perchloric acid doped silica is successfully used as an efficient mild catalyst for the synthesis of 4-aryl dihydropyrimidine-2(1H)- ones. This method offers significant advantages such as efficiency and mild reaction conditions.
One-pot synthesis of fused 3,4-dihydropyrimidin-2(1 H )-ones and thiones using a novel ionic liquid as an efficient and reusable catalyst: Improved protocol conditions for the Biginelli-like scaffolds
Janardhan, Banothu,Laxmi, Somarapu Vijaya,Rajitha, Bavanthu
experimental part, p. 93 - 97 (2012/08/08)
A novel ionic liquid with multi-SO3 H groups has been found to be an efficient acid catalyst for the one-pot three-component synthesis of fused 3,4-dihydropyrimidin-2(1 H )-ones and thiones under solvent free conditions. Good yields, short reaction times, straight forward workup, reusability of the catalyst and green conditions are the most obvious advantages of this methodology. Copyright by Walter de Gruyter.
