883106-52-3

Basic information

• Product Name: [1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: [1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER
• CAS NO: 883106-52-3
• Molecular Formula: C₁₆H₂₅N₃O₄S
• Molecular Weight: 355.45
• Mol File: 883106-52-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER(883106-52-3)
• EPA Substance Registry System: [1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER(883106-52-3)

Safety Data

• Hazardous Substances Data: 883106-52-3(Hazardous Substances Data)

Usage

Description

[1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER, with the molecular formula C19H28N4O4S, is a piperidine derivative featuring a carbamic acid ester group. [1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER is recognized for its unique chemical structure and pharmacological properties, which contribute to its potential as a building block in drug discovery and development. The presence of the tert-butyl ester group in the molecule enhances its stability and reactivity in various chemical reactions.

Uses

Used in Pharmaceutical Synthesis:
[1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique chemical structure allows it to be a valuable component in the development of new medications, potentially leading to the creation of novel therapeutics.
Used in Agrochemical Development:
In the agrochemical industry, [1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER is utilized as a key compound in the development of pesticides and other agricultural chemicals. Its incorporation into these products can enhance their effectiveness and selectivity, contributing to more efficient and targeted pest control solutions.
Used in Chemical Research:
[1-(4-AMINO-BENZENESULFONYL)-PIPERIDIN-4-YL]-CARBAMIC ACID TERT-BUTYL ESTER serves as a valuable research tool in the field of chemistry. Its unique properties make it an attractive candidate for studying various chemical reactions and mechanisms, potentially leading to advancements in synthetic methods and a deeper understanding of chemical processes.

Upstream product

• 1392490-93-5 [1-(4-nitrobenzenesulfonyl)piperidin-4-yl]carbamic acid tert-butyl ester 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 

Downstream Products

• 1414968-08-3 [1-(4-Methylamino-benzenesulfonyl)-piperidin-4-yl]-carbamic acid tert-butyl ester 
• 1414967-04-6 Tetrahydro-pyran-4-carboxylic acid [4-(4-acryloylamino-piperidine-1-sulfonyl)-phenyl]-methyl-amide 
• 1414968-09-4 (1-{4-[Methyl-(tetrahydro-pyran-4-carbonyl)-amino]-benzenesulfonyl}-piperidin-4-yl)-carbamic acid tert-butyl ester 
• 1414968-10-7 tetrahydro-pyran-4-carboxylic acid [4-(4-amino-piperidine-1-sulfonyl)-phenyl]-methyl-amide 
• 1033132-60-3 C₂₂H₂₈F₃N₅O₅S 

Relevant articles and documents

TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF

Certain compounds and pharmaceutically acceptable salts are provided herein. Also provided are pharmaceutical compositions comprising at least one compound or pharmaceutically acceptable salt therein and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain disease states responsive to the inhibition of transglutaminase TG2 activity are described. These disease states include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one compound or pharmaceutically acceptable salt thereof as a single active agent or administering at least one compound or pharmaceutically acceptable salt thereof in combination with one or more other therapeutic agents.