883111-37-3

Usage

Uses

Used in Pharmaceutical Research:
(2S,3S)-1-methyl-5-oxo-2-phenyltetrahydro-1H-pyrrolidine-3-carboxylic acid is used as a research compound for exploring its potential pharmacological properties. It is being investigated for its possible use in drug development, particularly for applications such as antiviral, anti-inflammatory, or antitumor agents. The specific stereochemistry of the compound may contribute to its effectiveness in these areas, making it a valuable candidate for further study and development in the pharmaceutical industry.

Upstream product

• 20178-20-5 (+/-)-(2R,3R)-1-methyl-5-oxo-2-phenyltetrahydro-1H-pyrrolidine-3-carboxylic acid 

Downstream Products

• 1020073-57-7 (1R)-1-(2,3,4-trichlorophenyl)ethyl (2S,3S)-1-methyl-5-oxo-2-phenyltetrahydro-1H-pyrrolidine-3-carboxylate 
• 1020073-58-8 (1S)-1-(2,3,4-trichlorophenyl)ethyl (2S,3S)-1-methyl-5-oxo-2-phenyltetrahydro-1H-pyrrolidine-3-carboxylate 
• 1020073-55-5 (1R)-2-oxo-1,2-diphenylethyl (2S,3S)-1-methyl-5-oxo-2-phenyltetrahydro-1H-pyrrolidine-3-carboxylate 
• 1020073-56-6 (1S)-2-oxo-1,2-diphenylethyl (2S,3S)-1-methyl-5-oxo-2-phenyltetrahydro-1H-pyrrolidine-3-carboxylate 
• 1020073-53-3 (2S,3S)-1-methyl-5-oxo-2-phenyl-N[(1R)-1-phenylethyl]tetrahydro-1H-pyrrolidine-3-carboxylamide 
• 1020073-54-4 (2S,3S)-1-methyl-5-oxo-2-phenyl-N[(1S)-1-phenylethyl]tetrahydro-1H-pyrrolidine-3-carboxylamide 

Relevant academic research and scientific papers

Enantiomers of (2R*,3R*)-1-methyl-5-oxo-2-phenyltetrahydro-1H-pyrrolidine-3-carboxylic acid as novel chiral resolving agents

A series of (2R*,3R*)-1-methyl-5-oxo-2-aryltetrahydro-1H-pyrrolidine-3-carboxylic acids were prepared and their structures were proven with X-ray crystallography. Racemic acid 5 has been resolved into enantiomers (2S,3S)-5 and (2R,3R)-5 by the formation of diastereomeric salts with brucine 9 and strychnidine 10, respectively. The ability of these enantiomers to serve as chiral discriminating agents was demonstrated by the chromatographic separation of diastereomeric amides and esters. Also, some preliminary results on the enantioselective reduction of prochiral imines with sodium borohydride modified by (2R,3R)-5 were collected.