883194-89-6

Upstream product

• 84228-44-4 methyl 4-amino-3-chlorobenzoate 

Downstream Products

• 1187367-16-3 4-[7-acetylamino-3-(6-methyl-pyridin-3-yl)-4,5-dihydro-pyrazolo[4,3-g]benzothiazol-1-yl]-3-chloro-benzoic acid methyl ester 
• 60481-45-0 4-hydrazino-3-chloro-benzoic acid 
• 952290-04-9 methyl 3-chloro-4-(7-ethylsulphanylcarbonylamino-3-pyridin-3-yl-4,5-dihydro-pyrazolo[4,3-g]benzothiazol-1-yl)-benzoate 

Relevant academic research and scientific papers

THIAZOLYL-DIHYDRO-INDAZOLE

The present invention relates to new thiazolyl-dihydro-indazoles of general formula (I) wherein the groups R1, R2 and R3 have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers and the mixtures thereof, and optionally the pharmacologically acceptable acid addition salts, solvates and hydrates thereof, and processes for preparing these thiazolyl-dihydro-indazoles and the use thereof as pharmaceutical compositions.

PI3 KINASES

The invention relates to the novel compounds of formula (1), which, due to their pharmaceutical effect as PI3 kinase modulators, are suitable for use in the therapy and treatment of inflammatory or allergic diseases. Examples of these diseases are inflammatory and allergic respiratory diseases, inflammatory diseases of the gastro-intestinal system and of the locomotor apparatus, inflammatory and allergic skin diseases, inflammatory ophthalmic diseases, diseases of the nasal mucosa, inflammatory or allergic autoimmune reactive conditions, or renal inflammations.