883229-11-6Relevant academic research and scientific papers
Synthesis and in vitro biological evaluation of carbon-11-labeled quinoline derivatives as new candidate PET radioligands for cannabinoid CB2 receptor imaging
Gao, Mingzhang,Wang, Min,Miller, Kathy D.,Hutchins, Gary D.,Zheng, Qi-Huang
experimental part, p. 2099 - 2106 (2010/06/12)
Cannabinoids have been recently proposed as a new family of potential antitumor agents, and cannabinoid receptor 2 (CB2) is believed to be over-expressed in tumor cells. This study was designed to develop new radioligands for imaging of CB2 receptor in ca
Synthesis and SAR studies of 2-oxoquinoline derivatives as CB2 receptor inverse agonists
Raitio, Katri H.,Savinainen, Juha R.,Veps?l?inen, Jouko,Laitinen, Jarmo T.,Poso, Antti,J?rvinen, Tomi,Nevalainen, Tapio
, p. 2022 - 2027 (2007/10/03)
The highly CB2 selective cannabinoid receptor inverse agonist, 7-methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3-carboxylic acid N-benzo[1,3]dioxol-5-ylmethyl)amide (JTE-907; 9b), served as the lead compound for investigating the structure-activity relat
