883231-20-7

Basic information

• Product Name: 2-BOC-AMINO PYRIDINE-5-BORONIC ACID
• Synonyms: 2-BOC-AMINO PYRIDINE-5-BORONIC ACID;6-(tert-butoxycarbonylamino)pyridin-3-ylboronic acid;(5-Borono-2-pyridinyl)-carbamic acid C-(1,1-dimethylethyl) ester;CarbaMic acid, N-(5-borono-2-pyridinyl)-, 1,1-diMethylethyl ester;6-(N-Boc-aMino)pyridine-3-boronic acid;Boc-6-AMinopyridine-3-boronic acid;6-(Boc-aMino)pyridine-3-boronic acid;2-(N-Boc-amino)pyridine-5-boronic acid
• CAS NO: 883231-20-7
• Molecular Formula: C₁₀H₁₅BN₂O₄
• Molecular Weight: 238.049
• Mol File: 883231-20-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.23
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.94±0.18(Predicted)
• CAS DataBase Reference: 2-BOC-AMINO PYRIDINE-5-BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BOC-AMINO PYRIDINE-5-BORONIC ACID(883231-20-7)
• EPA Substance Registry System: 2-BOC-AMINO PYRIDINE-5-BORONIC ACID(883231-20-7)

Safety Data

• Hazardous Substances Data: 883231-20-7(Hazardous Substances Data)

Usage

General Description

2-BOC-AMINO PYRIDINE-5-BORONIC ACID is a chemical compound with the formula C12H16BNO4. It is a boronic acid derivative with a Boc-protected amino group and a pyridine ring. 2-BOC-AMINO PYRIDINE-5-BORONIC ACID is commonly used as a building block in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. It is known for its ability to act as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, which are important in the development of new carbon-carbon bonds. Additionally, 2-BOC-AMINO PYRIDINE-5-BORONIC ACID has demonstrated potential as an inhibitor of certain enzymes and as a ligand in metal-catalyzed reactions. Overall, this compound has diverse applications in medicinal chemistry, materials science, and chemical biology.

InChI:InChI=1S/C10H15BN2O4/c1-10(2,3)17-9(14)13-8-5-4-7(6-12-8)11(15)16/h4-6,15-16H,1-3H3,(H,12,13,14)

Upstream product

• 159451-66-8 tert-butyl N-(5-bromopyridin-2-yl)carbamate 
• 207799-10-8 (4-bromopyridin-2-yl)-carbamic acid tert-butyl ester 
• 73183-34-3 bis(pinacol)diborane 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1072-97-5 5-bromo-2-pyridylamine 
• 5419-55-6 Triisopropyl borate 

Relevant articles and documents

MAP4K4 INHIBITORS

This invention relates to compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these compounds, for example in a method of treatmentof cardiac conditions.In particular, the present invention relates to compounds of formula (I):

OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS

The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, for example, multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms, for example, Bacterioides spp. and Clostridia spp. species, and acid fast organisms, for example, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.