883231-20-7

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
2-BOC-AMINO PYRIDINE-5-BORONIC ACID is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, leveraging its reactivity in organic synthesis to create complex molecules with potential therapeutic or pesticidal properties.
Used in Organic Synthesis:
In the field of organic synthesis, 2-BOC-AMINO PYRIDINE-5-BORONIC ACID is used as a versatile coupling partner for the formation of new carbon-carbon bonds through Suzuki-Miyaura cross-coupling reactions, which are crucial for constructing diverse organic compounds.
Used in Enzyme Inhibition:
2-BOC-AMINO PYRIDINE-5-BORONIC ACID is utilized as an inhibitor of certain enzymes, potentially contributing to the development of drugs that modulate enzyme activity for therapeutic purposes.
Used in Metal-Catalyzed Reactions:
As a ligand in metal-catalyzed reactions, 2-BOC-AMINO PYRIDINE-5-BORONIC ACID is employed to enhance the efficiency and selectivity of catalytic processes, which is vital for the synthesis of complex organic compounds in chemical biology and materials science.

InChI:InChI=1S/C10H15BN2O4/c1-10(2,3)17-9(14)13-8-5-4-7(6-12-8)11(15)16/h4-6,15-16H,1-3H3,(H,12,13,14)

Upstream product

• 159451-66-8 tert-butyl N-(5-bromopyridin-2-yl)carbamate 
• 207799-10-8 (4-bromopyridin-2-yl)-carbamic acid tert-butyl ester 
• 73183-34-3 bis(pinacol)diborane 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1072-97-5 5-bromo-2-pyridylamine 
• 5419-55-6 Triisopropyl borate 

Relevant academic research and scientific papers

MAP4K4 INHIBITORS

This invention relates to compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these compounds, for example in a method of treatmentof cardiac conditions.In particular, the present invention relates to compounds of formula (I):

High-selectivity CSF1R inhibitor, preparation method and pharmaceutical applications thereof

The invention relates to a high-selectivity CSF1R inhibitor with a structure represented by a formula (I), a preparation method and pharmaceutical applications thereof. According to the invention, thecompound can be widely applied to preparation of medicines for treating cancers, tumors, autoimmune diseases, metabolic diseases or metastatic diseases, especially for treating ovarian cancer, pancreatic cancer, prostate cancer, breast cancer, cervical cancer, glioblastoma, multiple myeloma, metabolic diseases, neurodegenerative diseases, primary tumor site metastasis or bone metastatic cancer, and is expected to be developed into a new generation of CSF1R inhibitor drugs.

OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS

The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, for example, multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms, for example, Bacterioides spp. and Clostridia spp. species, and acid fast organisms, for example, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.