883243-72-9

Basic information

• Product Name: N-(5-hydrazinocarbonylpentyl)-4-sulfamoylbenzamide
• Synonyms: N-(5-hydrazinocarbonylpentyl)-4-sulfamoylbenzamide
• CAS NO: 883243-72-9
• Molecular Weight: 328.392
• Mol File: 883243-72-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(5-hydrazinocarbonylpentyl)-4-sulfamoylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-hydrazinocarbonylpentyl)-4-sulfamoylbenzamide(883243-72-9)
• EPA Substance Registry System: N-(5-hydrazinocarbonylpentyl)-4-sulfamoylbenzamide(883243-72-9)

Safety Data

• Hazardous Substances Data: 883243-72-9(Hazardous Substances Data)

Upstream product

• 2780-89-4 methyl 6-aminohexanoate hydrochloride 
• 883243-70-7 6-(4-sulfamoylbenzoylamino)hexanoic acid methyl ester 
• 138-41-0 4-(aminosulfonyl)-benzoic acid 

Relevant articles and documents

Iminoboronates as Dual-Purpose Linkers in Chemical Probe Development

Chemical probes that covalently modify proteins of interest are powerful tools for the research of biological processes. Important in the design of a probe is the choice of reactive group that forms the covalent bond, as it decides the success of a probe. However, choosing the right reactive group is not a simple feat and methodologies for expedient screening of different groups are needed. We herein report a modular approach that allows easy coupling of a reactive group to a ligand. α-Nucleophile ligands are combined with 2-formylphenylboronic acid derived reactive groups to form iminoboronate probes that selectively label their target proteins. A transimination reaction on the labeled proteins with an α-amino hydrazide provides further modification, for example to introduce a fluorophore.