88329-77-5Relevant academic research and scientific papers
Generation of Azomethine Ylides via the Desilylation Reaction of Immonium Salts
Padwa, Albert,Haffmanns, Gunter,Tomas, Miguel
, p. 3314 - 3322 (2007/10/02)
Generation of intermediates having azomethine ylide reactivity was achieved by the reaction of several ethanol or thioimidate derivatives with methyl iodide followed by treatment of the resulting imine with (trimethylsilyl)methyl triflate.Desilylation of
CESIUM FLUORIDE INDUCED DESILYLATION REACTION OF IMMONIUM SALTS DERIVED FROM VINYLOGOUS AMIDES
Padwa, Albert,Haffmanns, Gunter,Tomas, Miguel
, p. 4303 - 4306 (2007/10/02)
The cesium fluoride induced desilylation reaction of immonium salts derived from amides, thioamides and vinylogous amides provides access to reactive azomethine ylides in synthetically useful yields.
NEW APPLICATIONS OF DIPOLAR CYCLOADDITION CHEMISTRY TOWARD THE SYNTHESIS OF HETEROCYCLES
Padwa, Albert,Chen, Yon-Yih,Koehler, Konrad F.,Tomas, Miguel
, p. 811 - 818 (2007/10/02)
A new method for the preparation of β-lactams has been developed.The protocol involves 1,3-dipolar cycloaddition of nitrones with nitro substituted alkenes followed by a subsequent reorganization of the resulting 5-nitroisoxazolidine isomer.The utilizatio
