88367-46-8Relevant academic research and scientific papers
Process for the preparation of (Z)-17α-halovinyl steroids
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, (2008/06/13)
(Z)-17α-halovinyl steroids of general Formula I STR1 wherein . . . . is a single bond or a double bond, V is a carbon-to-carbon bond or a methylene group, R1 is a hydrogen atom or a methyl group, X is a chlorine atom, a bromine atom or an iodine atom, and A symbolizes the remainder of the steroid molecule, are prepared by hydrogenating a 17α-haloethynyl steroid of formula II with diimide. STR2 wherein . . . , V, R1, X and A have the meanings given above. The compounds of Formula I include both known and novel compounds, all of which are pharmacologically active.
