88369-25-9Relevant academic research and scientific papers
On the way to α-methyl-α-amino acids; unusual elimination-addition in 3,3-disubstituted 1,4-benzodiazepin-2-ones and inversion of enantioselectivity in the lipase catalyzed acetylation
Avdagic, Amir,Sunjic, Vitomir
, p. 743 - 753 (2007/10/03)
(-)-3-Methanesulfoxymethyl-3-acetoxoymethyl-7-chloro-5-phenyl-1,4- benzodiazepin-2-one, (-)-2, reacts with ethanethiol in the presence of a strong base affording racemic elimination-addition product 3-ethylthiomethyl-7-chloro-5-phenyl-1,4-benzodiazepin-2-
Chiral 1,4-benzodiazepines. XII (1). Conformation in a solution of 7-chloro-5-phenyl-3(S)methyl-1,3-dihydro-2H-1,4-benzodiazepine
Decorte,Toso,Fajdiga,et al.
, p. 1321 - 1327 (2007/10/02)
Deuterium labeled congeners of 7-chloro-5-phenyl-3(S)-methyl-1,3-dihydro-2H-1,4-benzodiazepine (8), i.e. compounds 9 and 16-18 were prepared and their lis-nmr spectra run. For computational studies compounds 9 and 16 were chosen. The results of lis measur
