88374-37-2 Usage
Uses
Used in Pharmaceutical Industry:
(S)-(-)-N-(5-NITRO-2-PYRIDYL)PROLINOL is used as a chiral auxiliary and catalyst for enhancing the stereochemical control of reactions in the synthesis of pharmaceuticals. Its ability to promote high enantioselectivity makes it a valuable tool in creating enantiomerically pure compounds, which are essential for the development of effective and safe medications.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-(-)-N-(5-NITRO-2-PYRIDYL)PROLINOL is utilized as a catalyst for various organic reactions. Its role in the formation of chiral alcohols and amines is particularly noteworthy, as it contributes to the production of enantiomerically pure compounds that are vital for numerous applications, including the creation of biologically active molecules and advanced materials.
Used in Research and Development:
(S)-(-)-N-(5-NITRO-2-PYRIDYL)PROLINOL is also employed in research and development settings, where it serves as a key component in the exploration of new synthetic pathways and the discovery of novel compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 88374-37-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,3,7 and 4 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 88374-37:
(7*8)+(6*8)+(5*3)+(4*7)+(3*4)+(2*3)+(1*7)=172
172 % 10 = 2
So 88374-37-2 is a valid CAS Registry Number.
88374-37-2Relevant academic research and scientific papers
Twieg, R. J.,Dirk, C. W.
, p. 3537 - 3543 (1986)
The structure r=223.23, monoclinic, based on 930 reflections with F02>3.0?(F02)> of this compound reveals it to optimally satisfy many of the structural and symmetry restrictions required for optical second harmonic generation (SHG).The molecules are extraordinarily well aligned to optimize noncritically phase matched SHG with the amino nitrogen to nitro nitrogen charge transfer axis making an angle of 59.6 deg with the unique axis (b).The mean aromatic plane sits nearly perfectly in the (101) crystallographic plane which may be a natural cleavage surface through which normal propagation may produce noncritically phase matched SHG.Powder optical second harmonic generation measurements (λ =1.06μ; Nd-YAG laser) yield a value of 140.0x relative to powdered urea.Molecules related by a screw operation and the translation are intermolecularily hydrogen bonded .The structure is essentially isostructural to the earlier reported structure of N-(4-nitrophenyl)-(L)-prolinol (NPP) which appears to possess slightly enhanced second harmonic efficiency.
