88377-30-4Relevant academic research and scientific papers
Synthesis of novel fluorescent acridono- and thioacridono-18-crown-6 ligands
Huszthy, Péter,K?nt?s, Zoltán,Vermes, Borbála,Pintér, áron
, p. 4967 - 4975 (2007/10/03)
Novel fluorescent 18-crown-6 type ligands containing acridono and thioacridono units were synthesised. The acridono ligand was prepared by the oxidation of its acridino analogue, and also by the cyclisation of 4,5-dihydroxyacridine-9(10H)-one and tetraeth
Potential antitumor agents. 40. Orally active 4,5-disubstituted derivatives of amsacrine
Denny,Atwell,Baguley
, p. 363 - 367 (2007/10/02)
The DNA-intercalating agent amsacrine is an effective drug for the treatment of human leukemias and lymphomas but has minimal solid tumor activity. As a first step in identifying analogues with a wider spectrum of activity, a comparison was made of the in
