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CAS

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88378-59-0

Actinopyrone A is a gamma-pyrone compound that is isolated from a Streptomyces sp. It is characterized by its selective and potent activity against Helicobacter pylori, which is the primary cause of peptic ulcer disease. Originally identified for its coronary vasodilating activity, Actinopyrone A also exhibits weak activity against some Gram-positive bacteria and dermatophytes.

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  • 2-(10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl)-6-methoxy-3,5-dimethylpyran-4-one

    Cas No: 88378-59-0

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  • 88378-59-0 Structure

  • Basic information

    1. Product Name: ACTINOPYRONE A
    2. Synonyms: ACTINOPYRONE A;2-(10-Hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetrenyl)-6-methoxy-3,5-dimethyl-4H-pyran-4-one
    3. CAS NO:88378-59-0
    4. Molecular Formula: C25H36O4
    5. Molecular Weight: 400.55
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 88378-59-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: ACTINOPYRONE A(CAS DataBase Reference)
    10. NIST Chemistry Reference: ACTINOPYRONE A(88378-59-0)
    11. EPA Substance Registry System: ACTINOPYRONE A(88378-59-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 88378-59-0(Hazardous Substances Data)

88378-59-0 Usage

Uses

Used in Pharmaceutical Industry:
Actinopyrone A is used as an antibiotic agent for the treatment of peptic ulcer disease caused by Helicobacter pylori. Its selective and potent activity (MIC 0.0001 μg/ml) makes it a promising candidate for combating this bacterial infection.
Used in Cardiovascular Applications:
Actinopyrone A is used as a coronary vasodilator to improve blood flow in the coronary arteries. This property can be beneficial in treating various cardiovascular conditions, such as angina and other forms of heart disease.
Used in Antimicrobial Applications:
Although its activity is weak, Actinopyrone A can be used as an antimicrobial agent against some Gram-positive bacteria and dermatophytes. This can be useful in treating superficial infections and contributing to the development of new antimicrobial therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 88378-59-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,3,7 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 88378-59:
(7*8)+(6*8)+(5*3)+(4*7)+(3*8)+(2*5)+(1*9)=190
190 % 10 = 0
So 88378-59-0 is a valid CAS Registry Number.

88378-59-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name ACTINOPYRONE A

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:88378-59-0 SDS

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