88381-97-9Relevant academic research and scientific papers
A general catalytic allylation using allyltrimethoxysilane
Yamasaki, Shingo,Fujii, Kunihiko,Wada, Reiko,Kanai, Motomu,Shibasaki, Masakatsu
, p. 6536 - 6537 (2002)
A general and mild catalytic allylation of carbonyl compounds, applicable to aldehydes, ketones, and imines is developed using allyltrimethoxysilane as the allylating reagent. The reaction proceeds smoothly with 1-10 mol % of CuCl and TBAT in THF at ambie
Preparation and reactions of masked allylic organozinc reagents
Jones, Philip,Knochel, Paul
, p. 186 - 195 (2007/10/03)
Allylic zinc reagents have been prepared from sterically hindered homoallylic alcohols 10 and 13, using a novel fragmentation reaction of the corresponding zinc alkoxide, without any homocoupling products. These allylic zinc reagents react with a range of electrophiles in good to excellent yields. Substituted allylic zinc reagents have also been prepared in this manner. α-Substituted homoallylic alcohols 37, 46, and 51 give solely α- substituted products after the fragmentation-allylation sequence; these products are obtained not only regioselectively but also with extremely high anti diastereoselectivity. Likewise, γ-substituted homoallylic alcohols 57 and 58, undergo the fragmentation-allylation reaction to give γ-substituted products. The reaction has also been demonstrated to be catalytic in zinc salts.
Addition of Allylboronates to Schiff Bases and to Oximes
Hoffmann, Reinhard W.,Eichler, Guenter,Endesfelder, Andreas
, p. 2000 - 2007 (2007/10/02)
Clean addition of allylboronates of Type 3 to Schiff bases 2 leads to the secondary homoallylamines 4.Analogous addition to the oximes 9 results in the formation of the hydroxylamines 13.The latter allow the generation of the primary homoallylamines 14.
