883874-67-7

Basic information

• Product Name: 2-CHLORO-4-(2-METHYLPHENYL)PYRIDINE
• Synonyms: 2-CHLORO-4-(2-METHYLPHENYL)PYRIDINE
• CAS NO: 883874-67-7
• Molecular Formula: C12H10ClN
• Molecular Weight: 203.67
• Mol File: 883874-67-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 299.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.156±0.06 g/cm3(Predicted)
• PKA: 0.40±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-4-(2-METHYLPHENYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-(2-METHYLPHENYL)PYRIDINE(883874-67-7)
• EPA Substance Registry System: 2-CHLORO-4-(2-METHYLPHENYL)PYRIDINE(883874-67-7)

Safety Data

• Hazardous Substances Data: 883874-67-7(Hazardous Substances Data)

Upstream product

• 26452-80-2 2,4-dichloropyridine 
• 195062-59-0 2-methylphenylboronic acid pinacol ester 
• 153034-86-7 2-chloro-4-iodopyridine 
• 92929-20-9 4-(2-methylphenyl)pyridine 1-oxide 

Relevant articles and documents

Palladium-catalyzed c-4 selective coupling of 2,4-dichloropyridines and synthesis of pyridine-based dyes for live-cell imaging

An alternative process of Pd-catalyzed C-4 selective coupling of 2,4-dichloropyridines with boronic esters was developed, which afforded 24 examples of C-4 coupled pyridines in moderate to good yields. After further arylation, 21 examples of C-2, C-4 diarylated pyridines with a significant photophysical property were obtained, which were applied as pyridine-based dyes into live-cell imaging with good biocompatibility and low toxicity.

Arylpiperaszine derivatives, to the process for the production thereof and to the use thereof as therapeutic agents

The invention relates to compounds of the general formula (I): to the process for preparing them, and to the use thereof as a therapeutic agent.