883899-66-9

Upstream product

• 883899-69-2 2-[(4R,5S)-5-((R)-6-Ethynyl-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2,5-trimethyl-[1,3]dioxolan-4-yl]-ethanol 
• 883899-76-1 [(4R,5S)-5-((R)-6-Ethynyl-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2,5-trimethyl-[1,3]dioxolan-4-yl]-acetonitrile 
• 883899-77-2 [(4R,5R)-5-((R)-6-Ethynyl-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2,5-trimethyl-[1,3]dioxolan-4-yl]-acetaldehyde 
• 883899-78-3 Benzoic acid 2-[(4R,5S)-5-((R)-6-ethynyl-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2,5-trimethyl-[1,3]dioxolan-4-yl]-ethyl ester 

Downstream Products

• 883899-81-8 C₆₂H₁₀₆O₁₃Si₃ 
• 883899-70-5 C₅₀H₇₈O₁₃Si 

Relevant academic research and scientific papers

Convergent synthesis of the right-hand segment of ciguatoxin

A convergent synthesis of the right-hand half of ciguatoxin (the HIJKLM ring system) has been achieved with complete stereocontrol in the introduction of the stereocenters on the eight-membered I ring. Key steps are Sonogashira coupling, dicobalt complexation, intramolecular conjugate addition, and hydrogenation of an endo-olefin to provide the 39-α-methyl group.