883907-39-9

Upstream product

• 64248-63-1 3,5-difluorobenzonitrile 
• 14763-60-1 4-methanesulfonyl-phenol 
• 883907-35-5 3-fluoro-5-[4-(methanesulfonyl)phenoxy]benzonitrile 
• 136656-76-3 (S)-1-tert-butoxy-2-propanol 
• 883907-41-3 ({3-[(1S)-2-tert-butoxy-1-methylethoxy]-5-[4-(methylsulfonyl)phenoxy]benzoyl}oxy)(tert-butyl)ammonium 
• 883907-38-8 3-[(1S)-2-tert-butoxy-1-methylethoxy]-5-[4-(methylsulfonyl)phenoxy]benzonitrile 

Downstream Products

• 883907-41-3 ({3-[(1S)-2-tert-butoxy-1-methylethoxy]-5-[4-(methylsulfonyl)phenoxy]benzoyl}oxy)(tert-butyl)ammonium 
• 883907-34-4 3-[(1S)-2-tert-butoxy-1-methylethoxy]-N-(1-methyl-1H-pyrazol-3-yl)-5-[4-(methylsulfonyl)phenoxy]benzamide 

Relevant academic research and scientific papers

PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS

A process for making a compound of formula (I), said process comprising a) reaction of a compound of formula (II) with: i) a compound of formula (III) by nucleophilic aromatic substitution of X2 and ii) a compound of formula (IV) for example by

2-PHENYL SUBSTITUTED IMIDAZOL [4 , 5B] PYRIDINE/ PYRAZINE AND PURINE DERIVATIVES AS GLUCOKINASE MODULATORS

Compounds of Formula (I), wherein R1- R10, A and X1 to X3 are as described in the specification, and their salts and pro-drugs, are activators of glucokinase (GLK) and are thereby useful in the treatment of, for example, type 2 diabetes. Processes for preparing compounds of formula (I) are also described.