883976-56-5

Basic information

• Product Name: C₂₇H₃₃N₃O₄
• CAS NO: 883976-56-5
• Molecular Weight: 463.577
• Mol File: 883976-56-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₃N₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₃N₃O₄(883976-56-5)
• EPA Substance Registry System: C₂₇H₃₃N₃O₄(883976-56-5)

Safety Data

• Hazardous Substances Data: 883976-56-5(Hazardous Substances Data)

Upstream product

• 220598-39-0 3-allyl-3-hydroxy-1,3-dihydro-2H-indol-2-one 
• 98760-08-8 (1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester 
• 91-56-5 indole-2,3-dione 
• 883976-51-0 tert-butyl (2S,3R)-4-(allylamino)-3-hydroxy-1-phenylbutan-2-ylcarbamate 
• 883976-29-2 3-allyl-3-chloro-1,3-dihydro-indol-2-one 
• 883976-52-1 {3-[allyl-(3-allyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P′2-ligands

A series of novel oxyindole-derived HIV-1 protease inhibitors were designed and synthesized based upon our X-ray crystal structure of inhibitor 2 (TMC-114) bound to HIV-1 protease. The effects of substituents, spirocyclic rings, and ring sizes have been investigated. A number of inhibitors exhibited low nanomolar inhibitory potencies against HIV protease.