884-39-9

Basic information

• Product Name: L-(-)-α-Methyldopa (hydrochloride)
• Synonyms: L-(-)-α-Methyldopa (hydrochloride);MK-351 hydrochloride;3-hydroxy-a-methyl- L-Tyrosine hydrochloride
• CAS NO: 884-39-9
• Molecular Formula: C10H14ClNO4
• Molecular Weight: 247.67546
• Mol File: 884-39-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 441.6°C at 760 mmHg
• Flash Point: 220.9°C
• Appearance: /
• Vapor Pressure: 1.41E-08mmHg at 25°C
• CAS DataBase Reference: L-(-)-α-Methyldopa (hydrochloride)(CAS DataBase Reference)
• NIST Chemistry Reference: L-(-)-α-Methyldopa (hydrochloride)(884-39-9)
• EPA Substance Registry System: L-(-)-α-Methyldopa (hydrochloride)(884-39-9)

Safety Data

• Hazardous Substances Data: 884-39-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H13NO4.ClH/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6;/h2-4,12-13H,5,11H2,1H3,(H,14,15);1H/t10-;/m0./s1

Upstream product

• 1395919-79-5 (S)-3-(1-naphthoyl)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-2,2,4-trimethyloxazolidin-5-one 
• 1395919-80-8 (S)-2-(1-naphthamido)-3-(benzo[d][1,3]dioxol-5-yl)-2-methylpropanoic acid 
• 1369423-38-0 (R)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-4-methyl-2-phenyloxazol-5(4H)-one 

Downstream Products

• 62365-02-0 2-acetamidoethyl S-3-(3,4-dihydroxyphenyl)-2-methylalaninate 

Relevant articles and documents

BIOMARKERS RELATED TO PARKINSON'S DISEASE AND METHODS OF USING THE SAME

The present disclosure relates to the treatment of Parkinson's disease. The present disclosure provides, in some embodiments, methods of treating Parkinson's disease in a patient in need thereof. In some embodiments, the methods disclosed herein comprise

DECARBOXYLASE INHIBITORS FOR TREATING PARKINSON'S DISEASE

Provided are inhibitors of pathogenic, bacterial metabolite production and conjugates of the inhibitors. Also provided are pharmaceutical compositions containing the inhibitors or conjugates and methods of using the same.

Memory of chirality of tertiary aromatic amide: Application to the asymmetric synthesis of (S)-α-methylDOPA

We describe an original asymmetric synthesis of (S)-α-methylDOPA proceeding by the concept of memory of chirality, the only source of chirality being the starting d-alanine. The initial chirality of the amino acid is temporarily transferred to a dynamic axial chirality of a tertiary aromatic amide. The (S)-α-methylDOPA hydrochloride is obtained after four steps with 98% ee.