884345-83-9

Basic information

• Product Name: (4RS,8S)-10-benzyloxy-8-tert-butyldimethylsilyloxy-3,3-dimethyldec-1-en-4-ol
• Synonyms: (4RS,8S)-10-benzyloxy-8-tert-butyldimethylsilyloxy-3,3-dimethyldec-1-en-4-ol
• CAS NO: 884345-83-9
• Molecular Weight: 420.708
• Mol File: 884345-83-9.mol

Chemical Properties

• CAS DataBase Reference: (4RS,8S)-10-benzyloxy-8-tert-butyldimethylsilyloxy-3,3-dimethyldec-1-en-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (4RS,8S)-10-benzyloxy-8-tert-butyldimethylsilyloxy-3,3-dimethyldec-1-en-4-ol(884345-83-9)
• EPA Substance Registry System: (4RS,8S)-10-benzyloxy-8-tert-butyldimethylsilyloxy-3,3-dimethyldec-1-en-4-ol(884345-83-9)

Safety Data

• Hazardous Substances Data: 884345-83-9(Hazardous Substances Data)

Upstream product

• 870-63-3 prenyl bromide 
• 115114-87-9 (2R)-2-(2-benzyloxyethyl)oxirane 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 884345-82-8 (S)-7-benzyloxy-5-tert-butyldimethylsilyloxyheptan-1-ol 
• 884345-65-7 (S)-1-benzyloxy-3-tert-butyldimethylsilyloxyhept-6-ene 
• 884345-81-7 (S)-1-benzyloxyhept-6-en-3-ol 

Downstream Products

• 884345-67-9 2-(2-benzyloxy-ethyl)-6-(1,1-dimethyl-allyl)-3,4-dihydro-2H-pyran 
• 884345-84-0 (8S)-10-benzyloxy-8-hydroxy-3,3-dimethyldec-1-en-4-one 
• 884345-68-0 (2S,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2-methoxy-dihydro-pyran-3-one 
• 884345-85-1 (2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran 
• 884345-69-1 (2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2-methoxy-tetrahydro-pyran-3-ol 
• 884345-66-8 (8S)-10-benzyloxy-8-tert-butyldimethylsilyloxy-3,3-dimethyldec-1-en-4-one 

Relevant articles and documents

Some limitations of an approach to the assembly of bryostatins by ring-closing metathesis

Preliminary studies into the use of ring-closing metathesis (RCM) in a convergent approach for the total synthesis of bryostatins are described. An ester that would have provided an advanced intermediate for a synthesis of a 20-deoxybryostatin by a RCM wa

A preliminary evaluation of a metathesis approach to bryostatins

Preliminary investigations into the synthesis of bryostatins using ring-closing metathesis to form the C(16)-C(17) double bond led to a synthesis of the bryostatin analogue 51; precursors 26 and 52, which possess the geminal dimethyl group at C-18, did no