884489-28-5

Upstream product

• 62374-02-1 (E)-3,4-dichlorocinnamaldehyde 
• 20555-91-3 3,4-dichloroiodobenzene 
• 884489-20-7 diethyl [1-(3,4-dichlorophenyl)-3,3-diphenoxypropyl]phosphonate 
• 884489-24-1 diethyl [1-(3,4-dichlorophenyl)-2-formylethyl]phosphonate 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 

Downstream Products

• 884489-38-7 diethyl 3-(N-(benzyloxy)acetamido)-1-(3,4-dichlorophenyl)propylphosphonate 
• 884489-34-3 diethyl 3-(N-(benzyloxy)formamido)-1-(3,4-dichlorophenyl)propylphosphonate 
• 884489-43-4 diethyl [3-(N-hydroxyacetamido)-1-(3,4-dichlorophenyl)propyl]phosphonate 
• 884489-39-8 diethyl [1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propyl]phosphonate 
• 884489-32-1 [3-benzyloxyamino-1-(3,4-dichlorophenyl)-propyl]-phosphonic acid diethyl ester 

Relevant academic research and scientific papers

Synthesis of α-aryl-substituted and conformationally restricted fosmidomycin analogues as promising antimalarials

Fosmidomycin represents a new antimalarial drug that acts by inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an essential enzyme of the mevalonate-independent pathway of isoprenoid biosynthesis. This work describes the synthesis of a series