884498-59-3Relevant academic research and scientific papers
3,4-Disubstituted oxazolidin-2-ones as constrained ceramide analogs with anticancer activities
Singh, Alok,Ha, Hyun-Joon,Park, Jungchan,Kim, Jun Hee,Lee, Won Koo
, p. 6174 - 6181 (2011/12/02)
Heterocyclic analogs of ceramide as 3-alkanoyl or benzoyl-4-(1-hydroxy-2- enyl)-oxazolidin-2-ones were designed by binding of primary alcohol and amide in sphinogosine backbone as a carbamate. They were synthesized by addition of acyl halide to the common
Synthesis of constrained ceramide analogs and their potent antileukemic activities
Ha, Hyun-Joon,Hong, Myeng Chan,Ko, Seung Whan,Kim, Yong Woo,Lee, Won Koo,Park, Jungchan
, p. 1880 - 1883 (2007/10/03)
Constrained ceramide analogs were designed and synthesized by binding terminal alcohol and amine of ceramide with additional carbonyl functional group as 3-acetyl (3), 3-propionyl (4), 3-benzoyl (5), and 3-hexadecanoyl-4-(1- hydroxyhexadec-2-enyl)-oxazoli
Efficient synthesis of enantiomerically pure 2-acylaziridines: Facile syntheses of N-Boc-safingol, N-Boc-D-erythro-sphinganine, and N-Boc-spisulosine from a common intermediate
Yun, Jung Min,Sim, Tae Bo,Hahm, Heung Sik,Lee, Won Koo,Ha, Hyun-Joon
, p. 7675 - 7680 (2007/10/03)
Various enantiomerically pure 2-acylaziridines were prepared efficiently from the corresponding aziridine-2-carboxylate via Weinreb's amide and the subsequent treatment of organometallic compounds. The carbonyl group of those 2-acylaziridines was stereose
