88450-73-1

Upstream product

• 611-19-8 1-chloro-2-(chloromethyl)benzene 
• 95-51-2 o-chloroaniline 
• 10468-16-3 2-chloro-N-hydroxybenzenamine 
• 89-98-5 2-chloro-benzaldehyde 
• 878561-52-5 C-(2-chlorophenyl)-N-(2-chlorophenyl)nitrone 
• 17099-05-7 2-chloro-N-(2-chloro-benzyliden)-aniline 

Downstream Products

• 758640-21-0 N-Benzylaniline 
• 50844-93-4 5,6,5',6'-tetrahydro-[6,6']biphenanthridinyl 
• 229-87-8 phenanthridine 
• 98018-66-7 N-benzyl-2-chloroaniline 
• 133932-62-4 N-(2-chlorobenzyl)-N-(2-chlorophenyl)-benzamide 

Relevant academic research and scientific papers

Synthesis and reduction of nitrones of 2-chlorobenzaldehyde and their antifungal potential

Condensation of 2-chlorobenzaldehyde with phenylhydroxylamines resulted in the foripation of C-(2-chlorophenyl)-N-phenylnitrones (1a-6a) which were characterized on the basis of elemental analysis and spectral studies. Sodium borohydride reduction of the nitrones was carried out and the nitrones were screened for their antifungal potential against five phytopathogenic fungi.

The Photochemical Reactions of the Halogenated N-Benzylanilines. Mechanism of the Reactions

Several N-(2-halobenzyl)anilines and N-benzyl-2-haloanilines have been synthesized and their photochemical reactions studied.Upon irradiation, the aqueous acetonitrile solution of N-benzyl-2-chloroaniline was cyclized and reduced to give phenanthridine, 5,5',6,6'-tetrahydro-6,6'-biphenanthridyl (THBP), N-benzylaniline, and bibenzyl.Similar products were produced in the photochemical reactions of other halogenated N-benzylanilines, except iodo-substituted N-benzylanilines.No dimer (THBP) was produced from the iodo-substituted N-benzylanilines.Both singlet and triplet states are involved in the photochemical reactions of the haloarenes.

Method of topically treating inflammation

This invention describes a method of treating inflammation in warmblooded animals by topically administering an effective amount of benzylamine and its derivatives.