884512-56-5

Basic information

• Product Name: (R)-tert-butyl 3-(3-chloro-2-fluorobenzoyl)piperidine-1-carboxylate
• Synonyms: (R)-tert-butyl 3-(3-chloro-2-fluorobenzoyl)piperidine-1-carboxylate
• CAS NO: 884512-56-5
• Molecular Weight: 341.81
• Mol File: 884512-56-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (R)-tert-butyl 3-(3-chloro-2-fluorobenzoyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-tert-butyl 3-(3-chloro-2-fluorobenzoyl)piperidine-1-carboxylate(884512-56-5)
• EPA Substance Registry System: (R)-tert-butyl 3-(3-chloro-2-fluorobenzoyl)piperidine-1-carboxylate(884512-56-5)

Safety Data

• Hazardous Substances Data: 884512-56-5(Hazardous Substances Data)

Upstream product

• 884510-86-5 (R)-tert-butyl 3-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 1177419-07-6 C₆H₃ClFLi 
• 348-51-6 1-chloro-2-fluorobenzene 
• 163438-09-3 (R)-1-Boc-nipecotic acid 

Downstream Products

• 1177419-19-0 C₁₇H₂₃ClFNO₃ 
• 1177419-27-0 C₁₇H₂₃ClFNO₃ 

Relevant articles and documents

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Structure guided optimization of a series of nonpeptidic alkyl amine renin inhibitors allowed the rational incorporation of additional polar functionality. Replacement of the cyclohexylmethyl group occupying the S1 pocket with a (R)-(tetrahydropyran-3-yl)

RENIN INHIBITORS

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PIPERIDINE AND MORPHOLINE RENIN INHIBITORS

Described are compounds which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with renin activity. Also described are methods of use of these compounds for treating or ameliorating a renin mediated disorder in a subject.