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6-Amino-3-bromo-2-cyanopyridine is a heterocyclic chemical compound with the molecular formula C6H3BrN4. It features a pyridine ring structure with a bromine atom and a cyano group attached at different positions, making it a versatile intermediate in the synthesis of various organic compounds.

884541-48-4

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884541-48-4 Usage

Uses

Used in Pharmaceutical Industry:
6-Amino-3-bromo-2-cyanopyridine is used as a synthetic intermediate for the development of pharmaceutical compounds. Its unique structure allows for the creation of new molecules with potential therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical industry, 6-Amino-3-bromo-2-cyanopyridine serves as a key intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields.
Used in Material Development:
6-Amino-3-bromo-2-cyanopyridine is utilized in the development of new materials with specific properties. Its presence in these materials can influence characteristics such as stability, reactivity, and other desirable traits, making it valuable in material science research and applications.
Used in Dye Production:
6-Amino-3-bromo-2-cyanopyridine is also used in the production of dyes, where its unique structure contributes to the color and properties of the resulting dyes. Its use in dye manufacturing can lead to the creation of new, vibrant colors and improved dye performance in various applications.
Used in Medicinal Chemistry Research:
6-Amino-3-bromo-2-cyanopyridine is of interest in medicinal chemistry due to its potential pharmacological properties. Its biological activity may be harnessed in the development of new drugs and therapeutic agents, making it a valuable compound for research in this field.
However, it is crucial to handle 6-Amino-3-bromo-2-cyanopyridine with caution due to its potential hazards and toxicity. Proper safety measures should be taken to minimize risks associated with its use in various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 884541-48-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,4,5,4 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 884541-48:
(8*8)+(7*8)+(6*4)+(5*5)+(4*4)+(3*1)+(2*4)+(1*8)=204
204 % 10 = 4
So 884541-48-4 is a valid CAS Registry Number.

884541-48-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-amino-3-bromopyridine-2-carbonitrile

1.2 Other means of identification

Product number -
Other names 6-AMINO-3-BROMO-2-CYANOPYRIDINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:884541-48-4 SDS

884541-48-4Upstream product

884541-48-4Downstream Products

884541-48-4Relevant academic research and scientific papers

TYK2 INHIBITORS AND USES THEREOF

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Paragraph 00550; 00552, (2018/04/27)

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

FUSED MORPHOLINOPYRIMIDINES AND METHODS OF USE THEREOF

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Paragraph 1032, (2017/05/14)

The present disclosure relates to Fused Morpholinopyrimidines, pharmaceutical compositions comprising an effective amount of a Fused Morpholinopyrimidine and methods for using a Fused Morpholinopyrimidine in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of a Fused Morpholinopyrimidine.

multi-links class PI3K inhibitors (by machine translation)

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Paragraph 0261; 0262; 0263, (2016/10/09)

The invention belongs to the field of medical technology, in particular of formula (I) shown in multi-links class of PI3K inhibitors, its stereoisomers or its pharmaceutically acceptable salt thereof, wherein the R 1, R 2, R 3, R 4 or R 5 as defined in the specification; the invention also relates to methods of preparing such compounds, pharmaceutical compositions of these compounds in the preparation and treatment and/or prevention of proliferative diseases of the use of the medicament. (by machine translation)

FUSED MORPHOLINOPYRIMIDINES AND METHODS OF USE THEREOF

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Paragraph 0747, (2015/08/03)

The present disclosure relates to Fused Morpholinopyrimidines, pharmaceutical compositions comprising an effective amount of a Fused Morpholinopyrimidine and methods for using a Fused Morpholinopyrimidine in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of a Fused Morpholinopyrimidine.

Compounds and Their Use for Treatment of Amyloid Beta-Related Diseases

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Page/Page column 49-50, (2012/05/21)

The present invention relates to novel compounds of formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising said compounds, processes for making said compounds, and their use as medicaments for treatment and/or prevention of Aβ-related diseases.

OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION

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Page/Page column 196, (2012/03/11)

The present invention relates to compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

BETA-AMYLOID PET IMAGING AGENTS

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Page/Page column 11, (2008/06/13)

Novel derivatives of imidazopyridinylbenzeneamines and novel derivatives of benzothiazolylbenzeneamines are disclosed that offer improved behavior when used as imaging agents for positron emission tomography of beta-amyloids. Also disclosed is a palladium-catalyzed reaction scheme under microwave conditions for aryl thioethers in general that provides a high ratio of substitution relative to reduction and can be used for the imidazopyridinylbenzeneamine derivatives as well as other compounds of related structure.

Titanium(IV) chloride promoted syntheses of new imidazo[1,2-a]pyridine derivatives under microwave conditions

Cai, Lisheng,Brouwer, Chad,Sinclair, Kathryn,Cuevas, Jessica,Pike, Victor W.

, p. 133 - 145 (2007/10/03)

A new method is described for the synthesis of imidazo[1,2-a]pyridine derivatives from the reaction of 2-aminopyridines with α-haloketones. The critical reagent is titanium(IV) chloride, which appears to serve as a strong dehydrating agent to promote formation of putative Schiff base intermediates, which cyclize subsequently to form the products. The reactions were performed rapidly under microwave conditions. Multiple reaction conditions were evaluated, including reaction temperature, solvent and other Lewis acids. Various combinations of substitution patterns in both the α-haloketone and 2-aminopyridine substrates were examined to evaluate the scope of the reaction. The reaction is quite sensitive to substituents in both substrates, especially those with basicity or coordination ability. Georg Thieme Verlag Stuttgart.

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