884596-17-2Relevant academic research and scientific papers
First stereoselective synthesis of potassium aeschynomate and its no-natural stereomers
Claudel, Stéphanie,Olszewski, Tomasz Krzysztof,Mutzenardt, Pierre,Aroulanda, Christie,Coutrot, Philippe,Grison, Claude
, p. 1787 - 1798 (2007/10/03)
The synthesis of potassium aeshynomate and its non-natural stereomers was achieved using the Sharpless catalytic asymmetric dihydroxylation of (Z) or (E) vinylogous glycine as the key step. The resulting γ-amino α,β-dihydroxyester stereomer was deprotected and coupled with the caffeic acid to afford stereoselectively potassium aeshynomate or its stereomers. A detailed study of the NMR data of the different stereomers is reported that corrects the literature data.
