88462-22-0

Upstream product

• 99223-27-5 7-{(1R,2S,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(E)-(S)-3-(tert-butyl-dimethyl-silanyloxy)-3-cyclohexyl-propenyl]-5-oxo-cyclopentylsulfanyl}-heptanoic acid methyl ester 
• 438527-27-6 (4R)-tert-butyldimethylsilyloxy-2,3-epoxycyclopentanone 
• 82476-95-7 (1E)-(3S)-3-tert-butyldimethylsilyloxy-3-cyclohexyl-1-iodo-1-propene 
• 74842-61-8 (+)-(1E)-(3S)-3-cyclohexyl-3-hydroxyl-1-iodo-1-propene 
• 99223-17-3 4(R)-t-butyldimethylsilyloxy-2-(6-methoxycarbonylhexylthio)-2-cyclopentenone 
• 99223-15-1 methyl 7-mercaptoheptanoate 
• 71399-48-9 3-cyclohexyl-3RS-hydroxy-1-iodoprop-1E-ene 

Relevant academic research and scientific papers

Synthesis of 7-thiaprostaglandin E1 congeners: Potent inhibitors of platelet aggregation

Novel 7-thiaprostaglandin E1 derivatives and congeners were synthesized by a stepwise three-component coupling process, which involves the introduction of α-side chains (thiols) and β-side chains (organocopper reagents) into (R)-4-tert-butyldim