884651-52-9Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of substituted 3-alkylthio-4,5-diaryl-4H-1,2,4-triazoles as selective COX-2 inhibitors
Navidpour, Latifeh,Shafaroodi, Hamed,Abdi, Khosrou,Amini, Mohsen,Ghahremani, Mohammad H.,Dehpour, Ahmad Reza,Shafiee, Abbas
, p. 2507 - 2517 (2007/10/03)
A new type of 4,5-diaryl-4H-1,2,4-triazole, possessing C-3 thio and alkylthio (SH, SMe or SEt) substituents, was designed and synthesized for evaluation as selective cyclooxygenase-2 (COX-2) inhibitors with in vivo anti-inflammatory activity. The compound
