884738-96-9

Basic information

• Product Name: (3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine
• Synonyms: (3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine
• CAS NO: 884738-96-9
• Molecular Formula: C9H13N3
• Molecular Weight: 163.21962
• Mol File: 884738-96-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine(884738-96-9)
• EPA Substance Registry System: (3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine(884738-96-9)

Safety Data

• Hazardous Substances Data: 884738-96-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine is used as a key intermediate in organic synthesis for the development of various chemical compounds. Its unique structural features make it a valuable building block for creating novel molecules with potential applications in different industries.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine is used as a research compound for studying its interactions with biological targets. Its potential applications in medicinal chemistry and drug development are being explored due to its unique structural characteristics and stereochemistry.
Used in Medicinal Chemistry:
(3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine is employed as a starting material or a structural component in the design and synthesis of new drugs. Its versatility and unique features make it a promising candidate for the development of novel therapeutic agents.
Used in Drug Development:
(3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine is also used in drug development as a potential candidate for the treatment of various diseases. Its unique structural characteristics and stereochemistry allow for the exploration of its potential therapeutic effects and the development of new drugs with improved efficacy and safety profiles.
Overall, (3S)-1-(Pyridin-2-yl)pyrrolidin-3-amine is a versatile and valuable chemical compound with a wide range of potential applications in organic synthesis, pharmaceutical research, medicinal chemistry, and drug development. Its unique structural features and stereochemistry make it an attractive candidate for further exploration and utilization in various scientific and industrial fields.

Upstream product

• 109-09-1 2-chloropyridine 
• 208245-82-3 tert-butyl pyrrolidin-1-ylcarbamate 
• 372-48-5 2-fluoropyridine 
• 1029715-19-2 tert-butyl (1-(pyridin-2-yl)pyrrolidin-3-yl)carbamate 

Relevant articles and documents

COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO RET

Described herein are compounds of formula (I) that inhibit wild- type RET and its resistant mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.

HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS

Compounds of formula (I) [Formula should be inserted here] and a pharmaceutically acceptable salt thereof, wherein A, R1, R2, R3, R4, R5, R6, R7, R24, X, L, n and p are as defined in the specification, are useful for treating or preventing Mer tyrosine kinase receptor modulated disease or conditions. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.

PYRIMIDINEDIONE CARBOXAMIDE INHIBITORS OF ENDOTHELIAL LIPASE

The present invention provides compounds of Formula (I), as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicaments.

Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

Small molecule antagonists of the vanilloid receptor TRPV1 (also known as VR1) are disclosed. Pyrrolidinyl ureas such as 8 and 15 (SB-705498) emerged as lead compounds following optimisation of the previously described urea SB-452533. Pharmacological studies using electrophysiological and FLIPR-Ca2+-based assays showed that compounds such as 8 and 15 were potent antagonists versus the multiple chemical and physical modes of TRPV1 activation (namely capsaicin, acid and noxious heat). Furthermore, 15 possessed suitable developability properties to enable progression of this compound into in vivo studies and subsequently clinical development.

Substituted amine derivatives and methods of use

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Substituted amine derivatives and methods of use

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.