88488-99-7

Upstream product

• 154-23-4 catechin 
• 97233-47-1 cinnamtannin D₂ 
• 88038-00-0 6,8-dibromocatechin 
• 97233-06-2 epicatechin-(2β->O->7, 4β->8)-epicatechin-(4β->8)-catechin 

Downstream Products

• 100068-27-7 C₄₅H₃₅BrO₁₈ 
• 81410-22-2 6-bromo-3,3',4',5,7-penta-O-acetyl-(+)-catechin 
• 117820-43-6 6-bromo-8-iodocatechin 
• 69119-43-3 6-bromo-3-O-acetyl-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 78393-95-0 6-bromo-3',4',5,7-tetra-O-methyl-(+)-catechin 

Relevant academic research and scientific papers

IODINATION AND DEUTERATION OF CATECHIN DERIVATIVES

The preparation and 1H and 13C nuclear magnetic reonance spectra of ten monoiodocatechin derivatives are described.The iodination of catechin with N-iodosuccinimide (NIS) takes place regiospecifically at C-6 in acetone but preferentially at C-8 in dimethylformamide; both products can be derivatized at oxygen in alkali medium but lose iodine in the presence of acid. 3',4',5,7,-Tetra-O-methylcatechin reacts with NIS regiospecifically at C-8 while catechin pentaacetate resists iodination.The debromination of 6-bromo- and 6,8-dibromocatechin with sodium sulfite in CD3CN/D2O is accompained by H/D-exchange at C-6 and C-8.The synthesis of catechin pentaacetate from partially deuterated catechin and its conversion to terta-O-methylcatechin proceed without H/D-exchange and permit distinction between the H-6 and H-8 chemical shifts.

Synthesis of Condensed Tannins. Part 12. Direct Access to - and -all-2,3-cis-Procyanidin Derivatives from (-)-Epicatechin: Assessment of Bonding Positions in Oligomeric Analogues from Crataegus oxyacantha L.

Synthesis of methyl ester acetates of - and -all-2,3-cis-procyanidin biflavanoids is effected by oxidative functionalization of (-)-epicatechin tetramethyl ester with lead tetra-acetate, and condensation of the resultant 2,3-cis-flavan-3,4-diol