88489-56-9Relevant academic research and scientific papers
Trideuteromethylation Enabled by a Sulfoxonium Metathesis Reaction
Shen, Zuyuan,Zhang, Shilei,Geng, Huihui,Wang, Jiarui,Zhang, Xinyu,Zhou, Anqi,Yao, Cheng,Chen, Xiaobei,Wang, Wei
supporting information, p. 448 - 452 (2019/01/14)
A conceptually novel sulfoxonium metathesis reaction between TMSOI and cost-effective DMSO-d6 is developed for the efficient generation of a new trideuteromethylation reagent TDMSOI. The new reagent TDMSOI is produced highly efficiently by simply heating a mixture of TMSOI and DMSO-d6 and directly used for subsequent trideuteromethylation in a "one-pot" operation. The preparative power of the new versatile reagent and the "one-pot" protocol is demonstrated by its use to install the ?CD3 moiety into broad functionalities including phenols, thiophenols, acidic amines, and enolizable methylene units in high yield and at a useful level of deuteration (>87% D).
Fragmentation Selectivity in Electron Impact Ionization Mass Spectra of Substituted Dimethoxybenzenes
Nakata, Hisao,Jitsukawa, Fumie,Toyama, Hitomi,Kato, Yuko
, p. 720 - 723 (2007/10/02)
Several 1-X-substituted-3-methoxy-4-trideuteromethoxybenzenes were synthesized and their electron impact ionization mass spectra were measured with an ionizing energy of 20 eV.From the peak intensity ratio of and the fragmentation-dire
A RAMAN SPECTROSCOPIC STUDY OF THE LOW-FREQUENCY VIBRATIONS OF o-DIMETHOXYBENZENE AND ITS METHYL DEUTERATED ANALOGUES
Konschin, Henrik,Tylli, Henrik,Westermark, Bertel
, p. 279 - 288 (2007/10/02)
The low-frequency (100-400 cm-1) Raman spectra of liquid (at 300 K) and solid (at 130 K) veratrole (o-dimethoxybenzene), and its methyl deuterated analogues, have been measured.The methyl and methoxyl torsional transitions have been identified, and the corresponding rotational barriers have been determined.The interpretation of the spectra points to a conformationally mixed situation for solid veratrole, in which both planar and non-planar conformers may co-exist.
