88499-92-7 Usage
Uses
Used in Pharmaceutical Industry:
2-CDMQ is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential role in the development of new drugs. Its unique chemical structure allows for the creation of novel therapeutic agents that can address unmet medical needs.
Used in Agrochemical Industry:
In the agrochemical sector, 2-CDMQ is utilized as a precursor in the production of various agrochemicals, contributing to the development of effective pest control solutions and crop protection products.
Used in Medicinal Chemistry Research:
2-CDMQ is employed as a valuable research tool in medicinal chemistry, where it aids in the exploration of new chemical entities and the optimization of drug candidates. Its versatile structure makes it a promising candidate for the design and synthesis of innovative therapeutic agents.
Used in Organic Synthesis:
As an intermediate in organic synthesis, 2-CDMQ is utilized in the preparation of a wide range of organic compounds, including those with potential applications in various industries such as pharmaceuticals, materials science, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 88499-92-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,4,9 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 88499-92:
(7*8)+(6*8)+(5*4)+(4*9)+(3*9)+(2*9)+(1*2)=207
207 % 10 = 7
So 88499-92-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H10ClN/c1-7-3-4-9-8(2)6-11(12)13-10(9)5-7/h3-6H,1-2H3
88499-92-7Relevant academic research and scientific papers
Diastereoselective hydrogenation of substituted quinolines to enantiomerically pure decahydroquinolines
Heitbaum, Maja,Froehlich, Roland,Glorius, Frank
supporting information; experimental part, p. 357 - 362 (2010/05/19)
The stereoselective hydrogenation of auxiliary-substituted quinolines was used to build up saturated and partially saturated heterocycles. In a first step, the formation and diastereoselective hydrogenation of 2-oxazolidinone- substituted quinolines to 5,6,7,8-tetrahydroquinolines is reported. In this unprecedented process, stereocenters on the carbocyclic quinoline ring were formed with a dr of up to 89:11. Platinum oxide as a catalyst and trifluoroacetic acid as a solvent were found to be optimal for high levels of chemo- and stereoselectivity in this step. In a second hydrogenation step, the completely saturated decahydroquinolines with 4 newly formed stereocenters were obtained with enantioselectivities of up to 99%. Rhodium on carbon as a catalyst and acetic acid as a solvent gave the best results for this hydrogenation and allowed a traceless cleavage of the chiral auxiliary. Thus, this new method allows an efficient stereoselective synthesis of valuable 5,6,7,8-tetrahydro- and decahydroquinoline products.
