885048-92-0

Upstream product

• 885049-12-7 3-(dimethylarnino)-1-[6-(3-methoxyphenyl)imidazo[2,1-b][1,3]thiazol-5-yl]prop-2-en-1-one 
• 885049-13-8 tert-butyl (3R)-3-{[(Z)-amino(imino)methyl]amino}piperidine-1-carboxylate hydrochloride 
• 92754-06-8 6-(3-methoxyphenyl)imidazo[2,1-b]thiazole 
• 5000-65-7 2-bromo-3'-methoxyacetophenone 
• 188111-79-7 tert-butyl (3R)3-aminopiperidine-1-carboxylate 

Relevant academic research and scientific papers

RAF INHIBITORS AND THEIR USES

The present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAFV600E. The compounds are useful for the t

SYNTHESIS OF IMIDAZOOXAZOLE AND IMIDAZOTHIAZOLE INHIBITORS OF P38 MAP KINASE

An efficient route for the synthesis of formula (I), of imidazooxazole and imidazothiazole inhibitors of the p38 MAP kinase pathway, useful as therapeutics for disease conditions including inflammation and auto-immune responses is described.