885058-67-3

Basic information

• Product Name: phenylmethyl (1,2,3,4-tetrahydro-5,6-dimethoxynaphthalen-2-yl)carbamate
• CAS NO: 885058-67-3
• Molecular Weight: 341.407
• Mol File: 885058-67-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: phenylmethyl (1,2,3,4-tetrahydro-5,6-dimethoxynaphthalen-2-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: phenylmethyl (1,2,3,4-tetrahydro-5,6-dimethoxynaphthalen-2-yl)carbamate(885058-67-3)
• EPA Substance Registry System: phenylmethyl (1,2,3,4-tetrahydro-5,6-dimethoxynaphthalen-2-yl)carbamate(885058-67-3)

Safety Data

• Hazardous Substances Data: 885058-67-3(Hazardous Substances Data)

Upstream product

• 126674-76-8 5,6-dimethoxy-2-naphthalenecarboxylic acid 
• 885058-66-2 1,2,3,4-tetrahydro-5,6-dimethoxynaphthalene-2-carboxylic acid 
• 100-51-6 benzyl alcohol 

Downstream Products

• 21489-50-9 5,6-dimethoxy-2-aminotetrahydronaphthalene 

Relevant articles and documents

An alternative synthesis of the dopaminergic drug 2-amino-1,2,3,4- tetrahydronaphthalene-5,6-diol (5,6-ADTN)

Racemic 2-amino-1,2,3,4-tetrahydronaphthalene-5,6-diol (5,6-ADTN; 4) was synthesized from 5,6-dimethoxynaphthalene-2-carboxylic acid (14) in four steps (60% overall yield; Scheme). The crucial steps of the synthesis are Birch reduction of 14 to the valuable synthon 15, Curtius reaction and carbamate formation (16), hydrogenolysis (17), and demethylation to the biologically active hydrobromide salt 18 of 4.