885060-08-2 Usage
Uses
Used in Oncology:
ARRY-520 (R enantioMer) is used as an anticancer agent for its ability to effectively suppress tumor growth and induce apoptosis in cancer cells. It targets the kinesin spindle protein (KSP), a key component in the mitotic process, thereby disrupting cell division and exhibiting significant anti-cancer effects.
Used in Combination Therapy:
In the field of oncology, ARRY-520 (R enantioMer) is used as a component in combination therapies with other chemotherapy drugs. This approach has shown promising results in enhancing the anti-cancer effects of the compound, potentially overcoming resistance and improving treatment outcomes for patients with cancer.
Used in Clinical Trials:
ARRY-520 (R enantioMer) is utilized in clinical trials to evaluate its safety, efficacy, and optimal dosages for cancer treatment. These trials are crucial for understanding the compound's potential as a targeted therapy and for determining its role in future cancer treatment strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 885060-08-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,0,6 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 885060-08:
(8*8)+(7*8)+(6*5)+(5*0)+(4*6)+(3*0)+(2*0)+(1*8)=182
182 % 10 = 2
So 885060-08-2 is a valid CAS Registry Number.
885060-08-2Relevant academic research and scientific papers
MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF
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Page/Page column 94; 123-124, (2010/11/08)
This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.
